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Short-lived long noncoding RNAs as surrogate indicators for chemical stress in HepG2 cells and their degradation by nuclear RNases

Long noncoding RNAs (lncRNAs) are non-protein-coding transcripts >200 nucleotides in length that have been shown to play important roles in various biological processes. The mechanisms underlying the induction of lncRNA expression by chemical exposure remain to be determined. We identified a nove...

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Detalles Bibliográficos
Autores principales: Tani, Hidenori, Numajiri, Ayaka, Aoki, Motohide, Umemura, Tomonari, Nakazato, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937343/
https://www.ncbi.nlm.nih.gov/pubmed/31889167
http://dx.doi.org/10.1038/s41598-019-56869-y