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Antigen-driven selection of antibodies against SSA, SSB and the centromere ‘complex’, including a novel antigen, MIS12 complex, in human salivary glands

OBJECTIVES: Recent evidences have revealed that anti-SSA/SSB antibodies, the major autoantibodies in Sjögren's syndrome (SS), are produced in salivary glands. This study aims to clarify overall of autoantibody production at lesion site, including anti-centromere antibody (ACA)-positive SS. METH...

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Detalles Bibliográficos
Autores principales: Takeshita, Masaru, Suzuki, Katsuya, Kaneda, Yukari, Yamane, Humitsugu, Ikeura, Kazuhiro, Sato, Hidekazu, Kato, Shin, Tsunoda, Kazuyuki, Arase, Hisashi, Takeuchi, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937410/
https://www.ncbi.nlm.nih.gov/pubmed/31611218
http://dx.doi.org/10.1136/annrheumdis-2019-215862