Dual-specificity tyrosine phosphorylation-regulated kinase 1A ameliorates insulin resistance in neurons by up-regulating IRS-1 expression

Insulin resistance in the brain is a pathological mechanism that is shared between Alzheimer's disease (AD) and type 2 diabetes mellitus (T2DM). Although aberrant expression and phosphorylation of insulin receptor substrate 1 (IRS-1) contribute to insulin resistance, the underlying mechanism re...

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Detalles Bibliográficos
Autores principales: Tian, Shijiao, Jia, Wenming, Lu, Mei, Zhao, Juan, Sun, Xiulian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937568/
https://www.ncbi.nlm.nih.gov/pubmed/31723029
http://dx.doi.org/10.1074/jbc.RA119.010809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937568/
https://www.ncbi.nlm.nih.gov/pubmed/31723029
http://dx.doi.org/10.1074/jbc.RA119.010809

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