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Elucidating the expression and function of Numbl during cell adhesion-mediated drug resistance (CAM-DR) in multiple myeloma (MM)

BACKGROUND: Cell adhesion-mediated drug resistance (CAM-DR) is a major clinical problem that prevents successful treatment of multiple myeloma (MM). In particular, the expression levels of integrin β1 and its sub-cellular distribution (internalization and trafficking) are strongly associated with CA...

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Detalles Bibliográficos
Autores principales: Huang, Yuejiao, Huang, Xianting, Cheng, Chun, Xu, Xiaohong, Liu, Hong, Yang, Xiaojing, Yao, Li, Ding, Zongmei, Tang, Jie, He, Song, Wang, Yuchan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937660/
https://www.ncbi.nlm.nih.gov/pubmed/31888545
http://dx.doi.org/10.1186/s12885-019-6446-y