High expression of B7-H3 on stromal cells defines tumor and stromal compartments in epithelial ovarian cancer and is associated with limited immune activation

BACKGROUND: B7-H3 and B7-H4 are highly expressed by many human malignancies making them attractive immunotherapeutic targets. However, their expression patterns and immune contexts in epithelial ovarian cancer have not been well characterized. METHODS: We used flow cytometry, immunohistochemistry, a...

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Detalles Bibliográficos
Autores principales: MacGregor, Heather L., Sayad, Azin, Elia, Andrew, Wang, Ben X., Katz, Sarah Rachel, Shaw, Patricia A., Clarke, Blaise A., Crome, Sarah Q., Robert-Tissot, Celine, Bernardini, Marcus Q., Nguyen, Linh T., Ohashi, Pamela S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937725/
https://www.ncbi.nlm.nih.gov/pubmed/31892360
http://dx.doi.org/10.1186/s40425-019-0816-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937725/
https://www.ncbi.nlm.nih.gov/pubmed/31892360
http://dx.doi.org/10.1186/s40425-019-0816-5

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