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High expression of B7-H3 on stromal cells defines tumor and stromal compartments in epithelial ovarian cancer and is associated with limited immune activation
BACKGROUND: B7-H3 and B7-H4 are highly expressed by many human malignancies making them attractive immunotherapeutic targets. However, their expression patterns and immune contexts in epithelial ovarian cancer have not been well characterized. METHODS: We used flow cytometry, immunohistochemistry, a...
Autores principales: | MacGregor, Heather L., Sayad, Azin, Elia, Andrew, Wang, Ben X., Katz, Sarah Rachel, Shaw, Patricia A., Clarke, Blaise A., Crome, Sarah Q., Robert-Tissot, Celine, Bernardini, Marcus Q., Nguyen, Linh T., Ohashi, Pamela S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937725/ https://www.ncbi.nlm.nih.gov/pubmed/31892360 http://dx.doi.org/10.1186/s40425-019-0816-5 |
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