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Selection and characterization of single-stranded DNA aptamers against interleukin-5

Asthma as a chronic inflammatory disorder is associated with many cytokines like interleukin-5 (IL-5) which plays essential role in eosinophil differentiation and maturation. Accordingly, blockage of IL-5 using mepalizumab has been considered as a promising therapeutic approach for asthma. Despite t...

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Detalles Bibliográficos
Autores principales: Jamalvandi, Mina, Khanahmad, Hossein, Irani, Shiva, Bastaminezhad, Sayad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937751/
https://www.ncbi.nlm.nih.gov/pubmed/32038731
http://dx.doi.org/10.4103/1735-5362.272560