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Transcriptional activation of USP16 gene expression by NFκB signaling

Ubiquitin Specific Peptidase 16 (USP16) has been reported to contribute to somatic stem-cell defects in Down syndrome. However, how this gene being regulated is largely unknown. To study the mechanism underlying USP16 gene expression, USP16 gene promoter was cloned and analyzed by luciferase assay....

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Detalles Bibliográficos
Autores principales: Yang, Shou, Wang, Juelu, Guo, Shipeng, Huang, Daochao, Lorigados, Isabel Bestard, Nie, Xing, Lou, Dandan, Li, Yanhua, Liu, Mingjing, Kang, Yu, Zhou, Weihui, Song, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937840/
https://www.ncbi.nlm.nih.gov/pubmed/31888715
http://dx.doi.org/10.1186/s13041-019-0535-3