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Exome Sequencing Identifies Susceptibility Loci for Sarcoidosis Prognosis

Many sarcoidosis-associating immunological genes have been shown to be shared between other immune-mediated diseases. In Finnish sarcoidosis patients, good prognosis subjects more commonly have HLA-DRB1*03:01 and/or HLA-DRB1*04:01-DPB1*04:01 haplotype, but no marker for persistent disease have been...

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Detalles Bibliográficos
Autores principales: Lahtela, Elisa, Kankainen, Matti, Sinisalo, Juha, Selroos, Olof, Lokki, Marja-Liisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937869/
https://www.ncbi.nlm.nih.gov/pubmed/31921204
http://dx.doi.org/10.3389/fimmu.2019.02964