Distinct epigenetic features of tumor-reactive CD8+ T cells in colorectal cancer patients revealed by genome-wide DNA methylation analysis

BACKGROUND: Tumor-reactive CD8+ tumor-infiltrating lymphocytes (TILs) represent a subtype of T cells that can recognize and destroy tumor specifically. Understanding the regulatory mechanism of tumor-reactive CD8+ T cells has important therapeutic implications. Yet the DNA methylation status of this...

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Detalles Bibliográficos
Autores principales: Yang, Rui, Cheng, Sijin, Luo, Nan, Gao, Ranran, Yu, Kezhuo, Kang, Boxi, Wang, Li, Zhang, Qiming, Fang, Qiao, Zhang, Lei, Li, Chen, He, Aibin, Hu, Xueda, Peng, Jirun, Ren, Xianwen, Zhang, Zemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937914/
https://www.ncbi.nlm.nih.gov/pubmed/31892342
http://dx.doi.org/10.1186/s13059-019-1921-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937914/
https://www.ncbi.nlm.nih.gov/pubmed/31892342
http://dx.doi.org/10.1186/s13059-019-1921-y

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