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MEG3 promotes proliferation and inhibits apoptosis in osteoarthritis chondrocytes by miR-361-5p/FOXO1 axis

BACKGROUND: This study aimed to investigate the role of long non-coding RNA (lncRNA) maternally expressed 3 (MEG3) and related molecular mechanisms, in osteoarthritis (OA). METHODS: Cartilage tissues of OA patients and healthy volunteers were isolated and cultured. After transfection with the approp...

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Detalles Bibliográficos
Autores principales: Wang, Anying, Hu, Naixia, Zhang, Yefeng, Chen, Yuanzhen, Su, Changhui, Lv, Yao, Shen, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937924/
https://www.ncbi.nlm.nih.gov/pubmed/31888661
http://dx.doi.org/10.1186/s12920-019-0649-6