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Targeting soluble tumor necrosis factor as a potential intervention to lower risk for late-onset Alzheimer’s disease associated with obesity, metabolic syndrome, and type 2 diabetes

BACKGROUND: Insulin impairment and inflammation are two features common to type 2 diabetes and Alzheimer’s disease; however, the molecular and signaling interactions underlying this relationship are not well understood. Mounting evidence point to the associations between the disruption of metabolite...

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Detalles Bibliográficos
Autores principales: De Sousa Rodrigues, Maria Elizabeth, Houser, Madelyn C., Walker, Douglas I., Jones, Dean P., Chang, Jianjun, Barnum, Christopher J., Tansey, Malú G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937979/
https://www.ncbi.nlm.nih.gov/pubmed/31892368
http://dx.doi.org/10.1186/s13195-019-0546-4