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Targeting soluble tumor necrosis factor as a potential intervention to lower risk for late-onset Alzheimer’s disease associated with obesity, metabolic syndrome, and type 2 diabetes
BACKGROUND: Insulin impairment and inflammation are two features common to type 2 diabetes and Alzheimer’s disease; however, the molecular and signaling interactions underlying this relationship are not well understood. Mounting evidence point to the associations between the disruption of metabolite...
Autores principales: | De Sousa Rodrigues, Maria Elizabeth, Houser, Madelyn C., Walker, Douglas I., Jones, Dean P., Chang, Jianjun, Barnum, Christopher J., Tansey, Malú G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937979/ https://www.ncbi.nlm.nih.gov/pubmed/31892368 http://dx.doi.org/10.1186/s13195-019-0546-4 |
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