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Profiling of the germline mutation BRCA1: p.Ile1845fs in a large cohort of Han Chinese breast cancer

BACKGROUND: Breast cancer is a one of the malignant carcinomas partially caused by genetic risk factors. Germline BRCA1 gene mutations are reportedly associated with breast cancers. Identification of BRCA1 mutations greatly improves the preventive strategies and management of breast cancer. The aim...

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Detalles Bibliográficos
Autores principales: Wu, Yu, Zhang, Huanhuan, Weng, Xiaoling, Wang, Honglian, Zhou, Qinghua, Wu, Ying, Shen, Yi, Hu, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937991/
https://www.ncbi.nlm.nih.gov/pubmed/31908633
http://dx.doi.org/10.1186/s41065-019-0115-7