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Plasma membrane localization of MLC1 regulates cellular morphology and motility

BACKGROUND: Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare form of infantile-onset leukodystrophy. The disorder is caused primarily by mutations of MLC1 that leads to a series of phenotypic outcomes including vacuolation of myelin and astrocytes, subcortical cysts, brain...

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Detalles Bibliográficos
Autores principales: Hwang, Junmo, Vu, Hung M., Kim, Min-Sik, Lim, Hyun-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938022/
https://www.ncbi.nlm.nih.gov/pubmed/31888684
http://dx.doi.org/10.1186/s13041-019-0540-6