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Differential Expression of Human N-Alpha-Acetyltransferase 40 (hNAA40), Nicotinamide Phosphoribosyltransferase (NAMPT) and Sirtuin-1 (SIRT-1) Pathway in Obesity and T2DM: Modulation by Metformin and Macronutrient Intake

BACKGROUND: Interactions between environmental factors, such as diet and lifestyle, and metabolic pathways are pivotal in understanding aging mechanisms. hNAA40, Nicotinamide phosphoribosyltransferase (NAMPT), and NAD-dependent protein deacetylase sirtuin-1 (SIRT-1) have been shown to exert importan...

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Detalles Bibliográficos
Autores principales: Alshahrani, Awad, AlDubayee, Mohammed, Zahra, Mahmoud, Alsebayel, Firas M, Alammari, Nawaf, Alsudairy, Faisal, Almajed, Muath, Aljada, Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938199/
https://www.ncbi.nlm.nih.gov/pubmed/31920356
http://dx.doi.org/10.2147/DMSO.S228591