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EIPR1 controls dense-core vesicle cargo retention and EARP complex localization in insulin-secreting cells

Dense-core vesicles (DCVs) are secretory vesicles found in neurons and endocrine cells. DCVs package and release cargoes including neuropeptides, biogenic amines, and peptide hormones. We recently identified the endosome-associated recycling protein (EARP) complex and the EARP-interacting-protein EI...

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Detalles Bibliográficos
Autores principales: Topalidou, Irini, Cattin-Ortolá, Jérôme, Hummer, Blake, Asensio, Cedric S., Ailion, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938272/
https://www.ncbi.nlm.nih.gov/pubmed/31721635
http://dx.doi.org/10.1091/mbc.E18-07-0469