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A systems approach identifies Enhancer of Zeste Homolog 2 (EZH2) as a protective factor in epilepsy

Complex neurological conditions can give rise to large scale transcriptomic changes that drive disease progression. It is likely that alterations in one or a few transcription factors or cofactors underlie these transcriptomic alterations. Identifying the driving transcription factors/cofactors is a...

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Detalles Bibliográficos
Autores principales: Khan, Nadia, Schoenike, Barry, Basu, Trina, Grabenstatter, Heidi, Rodriguez, Genesis, Sindic, Caleb, Johnson, Margaret, Wallace, Eli, Maganti, Rama, Dingledine, Raymond, Roopra, Avtar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938365/
https://www.ncbi.nlm.nih.gov/pubmed/31891591
http://dx.doi.org/10.1371/journal.pone.0226733