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Opioids modulate an emergent rhythmogenic process to depress breathing

How mammalian neural circuits generate rhythmic activity in motor behaviors, such as breathing, walking, and chewing, remains elusive. For breathing, rhythm generation is localized to a brainstem nucleus, the preBötzinger Complex (preBötC). Rhythmic preBötC population activity consists of strong ins...

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Detalles Bibliográficos
Autores principales: Sun, Xiaolu, Thörn Pérez, Carolina, Halemani D, Nagaraj, Shao, Xuesi M, Greenwood, Morgan, Heath, Sarah, Feldman, Jack L, Kam, Kaiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938398/
https://www.ncbi.nlm.nih.gov/pubmed/31841107
http://dx.doi.org/10.7554/eLife.50613