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[(18)F]SPA-RQ/PET Study of NK1 receptors in the Whole Body of Guinea Pig and Rat

There is a substantial interest in the development of NK1 substance P antagonists as potential treatments for various neuropsychiatric and somatic disorders. The aim of this study was to determine whether [(18)F]SPA-RQ can be utilized as a tool for studying the whole body distribution and function o...

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Detalles Bibliográficos
Autores principales: Grönroos, Tove J., Forsback, Sarita, Eskola, Olli, Bergman, Jörgen, Marjamäki, Päivi, Löyttyniemi, Eliisa, Hietala, Jarmo, Haaparanta-Solin, Merja, Solin, Olof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938475/
https://www.ncbi.nlm.nih.gov/pubmed/31892711
http://dx.doi.org/10.1038/s41598-019-56848-3