Therapeutic effects of statins against lung adenocarcinoma via p53 mutant-mediated apoptosis

The p53 gene is an important tumour suppressor gene. Mutant p53 genes account for about half of all lung cancer cases. There is increasing evidence for the anti-tumour effects of statins via inhibition of the mevalonate pathway. We retrospectively investigated the correlation between statin use and...

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Detalles Bibliográficos
Autores principales: Chou, Cheng-Wei, Lin, Ching-Heng, Hsiao, Tzu-Hung, Lo, Chia-Chien, Hsieh, Chih-Ying, Huang, Cheng-Chung, Sher, Yuh-Pyng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938497/
https://www.ncbi.nlm.nih.gov/pubmed/31892709
http://dx.doi.org/10.1038/s41598-019-56532-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938497/
https://www.ncbi.nlm.nih.gov/pubmed/31892709
http://dx.doi.org/10.1038/s41598-019-56532-6

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