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Therapeutic effects of statins against lung adenocarcinoma via p53 mutant-mediated apoptosis
The p53 gene is an important tumour suppressor gene. Mutant p53 genes account for about half of all lung cancer cases. There is increasing evidence for the anti-tumour effects of statins via inhibition of the mevalonate pathway. We retrospectively investigated the correlation between statin use and...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938497/ https://www.ncbi.nlm.nih.gov/pubmed/31892709 http://dx.doi.org/10.1038/s41598-019-56532-6 |