Innate immune responses through Toll-like receptor 3 require human-antigen-R-mediated Atp6v0d2 mRNA stabilization

Toll-like receptor 3 (TLR3) recognizes double-stranded RNA derived from virus and its synthetic analogue, polyinosinic–polycytidylic acid [poly(I:C)]. Upon poly(I:C) binding, TLR3 activates transcription factors to express inflammatory cytokines and type I interferon. TLR3 is located in the endosome...

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Detalles Bibliográficos
Autores principales: Zainol, Mohd Izwan Bin, Kawasaki, Takumi, Monwan, Warunthorn, Murase, Motoya, Sueyoshi, Takuya, Kawai, Taro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938500/
https://www.ncbi.nlm.nih.gov/pubmed/31892731
http://dx.doi.org/10.1038/s41598-019-56914-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938500/
https://www.ncbi.nlm.nih.gov/pubmed/31892731
http://dx.doi.org/10.1038/s41598-019-56914-w

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