Modification of an aggressive model of Alport Syndrome reveals early differences in disease pathogenesis due to genetic background

The link between mutations in collagen genes and the development of Alport Syndrome has been clearly established and a number of animal models, including knock-out mouse lines, have been developed that mirror disease observed in patients. However, it is clear from both patients and animal models tha...

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Detalles Bibliográficos
Autores principales: Falcone, Sara, Wisby, Laura, Nicol, Thomas, Blease, Andrew, Starbuck, Becky, Parker, Andrew, Sanderson, Jeremy, Brown, Steve D. M., Scudamore, Cheryl L., Pusey, Charles D., Tam, Frederick W. K., Potter, Paul K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938516/
https://www.ncbi.nlm.nih.gov/pubmed/31892712
http://dx.doi.org/10.1038/s41598-019-56837-6

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