Cargando…

Short- and medium-term impact of bariatric surgery on the activities of CYP2D6, CYP3A4, CYP2C9, and CYP1A2 in morbid obesity

Morbid obesity and bariatric surgery induce anatomical, physiological and metabolic alterations that may alter the body’s disposition of drugs. Current literature on this topic is limited and sometimes inconsistent. Cytochrome P450 (CYP) is a superfamily of enzymes that metabolize around 75% of all...

Descripción completa

Detalles Bibliográficos
Autores principales: Rodríguez-Morató, Jose, Goday, Albert, Langohr, Klaus, Pujadas, Mitona, Civit, Ester, Pérez-Mañá, Clara, Papaseit, Esther, Ramon, Jose Manuel, Benaiges, David, Castañer, Olga, Farré, Magí, de la Torre, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938522/
https://www.ncbi.nlm.nih.gov/pubmed/31892725
http://dx.doi.org/10.1038/s41598-019-57002-9