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Notch3 Promotes Prostate Cancer-Induced Bone Lesion Development via MMP-3

Prostate cancer metastases primarily localize in the bone where they induce a unique osteoblastic response. Elevated Notch activity is associated with high-grade disease and metastasis. To address how Notch affects prostate cancer bone lesions, we manipulated Notch expression in mouse tibia xenograf...

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Detalles Bibliográficos
Autores principales:	Ganguly, Sourik S., Hostetter, Galen, Tang, Lin, Frank, Sander B., Saboda, Kathylynn, Mehra, Rohit, Wang, Lisha, Li, Xiaohong, Keller, Evan T., Miranti, Cindy K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938550/ https://www.ncbi.nlm.nih.gov/pubmed/31467432 http://dx.doi.org/10.1038/s41388-019-0977-1

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