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Transient receptor potential ankyrin 1 promoter methylation and peripheral pain sensitivity in Crohn’s disease

BACKGROUND: Crohn’s disease is a chronic inflammatory disorder of the gastrointestinal tract associated with abdominal pain and diarrhea. Pain caused by Crohn’s disease likely involves neurogenic inflammation which seems to involve the ion channel transient receptor potential ankyrin 1 (TRPA1). Sinc...

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Detalles Bibliográficos
Autores principales: Gombert, Sara, Rhein, Mathias, Winterpacht, Andreas, Münster, Tino, Hillemacher, Thomas, Leffler, Andreas, Frieling, Helge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938615/
https://www.ncbi.nlm.nih.gov/pubmed/31892361
http://dx.doi.org/10.1186/s13148-019-0796-9