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Control of noncoding RNA production and histone levels by a 5′ tRNA fragment

Small RNAs derived from mature tRNAs, referred to as tRNA fragments or “tRFs,” are an emerging class of regulatory RNAs with poorly understood functions. We recently identified a role for one specific tRF—5′ tRF-Gly-GCC, or tRF-GG—as a repressor of genes associated with the endogenous retroelement M...

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Detalles Bibliográficos
Autores principales: Boskovic, Ana, Bing, Xin Yang, Kaymak, Ebru, Rando, Oliver J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938667/
https://www.ncbi.nlm.nih.gov/pubmed/31831626
http://dx.doi.org/10.1101/gad.332783.119