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Set1/COMPASS repels heterochromatin invasion at euchromatic sites by disrupting Suv39/Clr4 activity and nucleosome stability

Protection of euchromatin from invasion by gene-repressive heterochromatin is critical for cellular health and viability. In addition to constitutive loci such as pericentromeres and subtelomeres, heterochromatin can be found interspersed in gene-rich euchromatin, where it regulates gene expression...

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Detalles Bibliográficos
Autores principales: Greenstein, R.A., Barrales, Ramon R., Sanchez, Nicholas A., Bisanz, Jordan E., Braun, Sigurd, Al-Sady, Bassem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938669/
https://www.ncbi.nlm.nih.gov/pubmed/31805521
http://dx.doi.org/10.1101/gad.328468.119