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Set1/COMPASS repels heterochromatin invasion at euchromatic sites by disrupting Suv39/Clr4 activity and nucleosome stability
Protection of euchromatin from invasion by gene-repressive heterochromatin is critical for cellular health and viability. In addition to constitutive loci such as pericentromeres and subtelomeres, heterochromatin can be found interspersed in gene-rich euchromatin, where it regulates gene expression...
Autores principales: | Greenstein, R.A., Barrales, Ramon R., Sanchez, Nicholas A., Bisanz, Jordan E., Braun, Sigurd, Al-Sady, Bassem |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938669/ https://www.ncbi.nlm.nih.gov/pubmed/31805521 http://dx.doi.org/10.1101/gad.328468.119 |
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