CDK7 regulates organ size and tumor growth by safeguarding the Hippo pathway effector Yki/Yap/Taz in the nucleus

Hippo signaling controls organ size and tumor progression through a conserved pathway leading to nuclear translocation of the transcriptional effector Yki/Yap/Taz. Most of our understanding of Hippo signaling pertains to its cytoplasmic regulation, but how the pathway is controlled in the nucleus re...

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Detalles Bibliográficos
Autores principales: Cho, Yong Suk, Li, Shuang, Wang, Xiaohui, Zhu, Jian, Zhuo, Shu, Han, Yuhong, Yue, Tao, Yang, Yingzi, Jiang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938674/
https://www.ncbi.nlm.nih.gov/pubmed/31857346
http://dx.doi.org/10.1101/gad.333146.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938674/
https://www.ncbi.nlm.nih.gov/pubmed/31857346
http://dx.doi.org/10.1101/gad.333146.119

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