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Polymorphism in ASCL1 target gene DDC is associated with clinical outcomes of small cell lung cancer patients

BACKGROUND: Achaete‐scute homolog 1 (ASCL1) is a basic helix‐loop‐helix transcription factor and is essential in the differentiation of neuroendocrine cells and neural tissues. ASCL1 is frequently overexpressed in small cell lung cancer (SCLC) and plays a crucial role in the pathogenesis of SCLC. ME...

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Detalles Bibliográficos
Autores principales: Kim, Ji Hyun, Lee, Shin Yup, Choi, Jin Eun, Do, Sook Kyung, Lee, Jang Hyuck, Hong, Mi Jeong, Kang, Hyo‐Gyoung, Lee, Won Kee, Shin, Kyung Min, Jeong, Ji Yun, Choi, Sun Ha, Lee, Yong Hoon, Seo, Hyewon, Yoo, Seung Soo, Lee, Jaehee, Cha, Seung Ick, Kim, Chang Ho, Park, Jae Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938757/
https://www.ncbi.nlm.nih.gov/pubmed/31691490
http://dx.doi.org/10.1111/1759-7714.13212