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Polymorphism in ASCL1 target gene DDC is associated with clinical outcomes of small cell lung cancer patients
BACKGROUND: Achaete‐scute homolog 1 (ASCL1) is a basic helix‐loop‐helix transcription factor and is essential in the differentiation of neuroendocrine cells and neural tissues. ASCL1 is frequently overexpressed in small cell lung cancer (SCLC) and plays a crucial role in the pathogenesis of SCLC. ME...
Autores principales: | Kim, Ji Hyun, Lee, Shin Yup, Choi, Jin Eun, Do, Sook Kyung, Lee, Jang Hyuck, Hong, Mi Jeong, Kang, Hyo‐Gyoung, Lee, Won Kee, Shin, Kyung Min, Jeong, Ji Yun, Choi, Sun Ha, Lee, Yong Hoon, Seo, Hyewon, Yoo, Seung Soo, Lee, Jaehee, Cha, Seung Ick, Kim, Chang Ho, Park, Jae Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons Australia, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938757/ https://www.ncbi.nlm.nih.gov/pubmed/31691490 http://dx.doi.org/10.1111/1759-7714.13212 |
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