Cargando…

Liver Activation of Hepatocellular Nuclear Factor-4α by Small Activating RNA Rescues Dyslipidemia and Improves Metabolic Profile

Non-alcoholic fatty liver disease (NAFLD) culminates in insulin resistance and metabolic syndrome. Because there are no approved pharmacological treatment agents for non-alcoholic steatohepatitis (NASH) and NAFLD, different signaling pathways are under investigation for drug development with the foc...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Kai-Wen, Reebye, Vikash, Czysz, Katherine, Ciriello, Simona, Dorman, Stephanie, Reccia, Isabella, Lai, Hong-Shiee, Peng, Ling, Kostomitsopoulos, Nikos, Nicholls, Joanna, Habib, Robert S., Tomalia, Donald A., Sætrom, Pål, Wilkes, Edmund, Cutillas, Pedro, Rossi, John J., Habib, Nagy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938799/
https://www.ncbi.nlm.nih.gov/pubmed/31877412
http://dx.doi.org/10.1016/j.omtn.2019.10.044