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Vitamin C controls neuronal necroptosis under oxidative stress

Under physiological conditions, vitamin C is the main antioxidant found in the central nervous system and is found in two states: reduced as ascorbic acid (AA) and oxidized as dehydroascorbic acid (DHA). However, under pathophysiological conditions, AA is oxidized to DHA. The oxidation of AA and sub...

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Detalles Bibliográficos
Autores principales: Ferrada, Luciano, Barahona, María Jose, Salazar, Katterine, Vandenabeele, Peter, Nualart, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938857/
https://www.ncbi.nlm.nih.gov/pubmed/31926631
http://dx.doi.org/10.1016/j.redox.2019.101408