Novel double functional protection of cephalostatin analogues using a gas-free chlorination method

Herewith, we report on a method that allows to simultaneously protect both the ∆(14,15) bond and the carbonyl group of the symmetrical bis-steroidal diketone 2. We found that environmentally friendly and gas-free chlorination is ideally suited to achieve this goal. This method was discovered during...

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Detalles Bibliográficos
Autores principales: Nawasreh, Mansour, Kirschning, Andreas, Duddeck, Helmut, Dräger, Gerald, Fenske, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938862/
https://www.ncbi.nlm.nih.gov/pubmed/31909240
http://dx.doi.org/10.1016/j.heliyon.2019.e03025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938862/
https://www.ncbi.nlm.nih.gov/pubmed/31909240
http://dx.doi.org/10.1016/j.heliyon.2019.e03025

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