Micro-dystrophin Gene Therapy Partially Enhances Exercise Capacity in Older Adult mdx Mice

Micro-dystrophin (μDys) gene therapeutics can improve striated muscle structure and function in different animal models of Duchenne muscular dystrophy. Most studies, however, used young mdx mice that lack a pronounced dystrophic phenotype, short treatment periods, and limited muscle function tests....

Descripción completa

Detalles Bibliográficos
Autores principales: Rodgers, Buel D., Bishaw, Yemeserach, Kagel, Denali, Ramos, Julian N., Maricelli, Joseph W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939027/
https://www.ncbi.nlm.nih.gov/pubmed/31909085
http://dx.doi.org/10.1016/j.omtm.2019.11.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939027/
https://www.ncbi.nlm.nih.gov/pubmed/31909085
http://dx.doi.org/10.1016/j.omtm.2019.11.015

Ejemplares similares