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Micro-dystrophin Gene Therapy Partially Enhances Exercise Capacity in Older Adult mdx Mice
Micro-dystrophin (μDys) gene therapeutics can improve striated muscle structure and function in different animal models of Duchenne muscular dystrophy. Most studies, however, used young mdx mice that lack a pronounced dystrophic phenotype, short treatment periods, and limited muscle function tests....
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939027/ https://www.ncbi.nlm.nih.gov/pubmed/31909085 http://dx.doi.org/10.1016/j.omtm.2019.11.015 |