Pharmacological antagonism of the incretin system protects against diet-induced obesity

OBJECTIVE: Glucose-dependent insulinotropic polypeptide is an intestinally derived hormone that is essential for normal metabolic regulation. Loss of the GIP receptor (GIPR) through genetic elimination or pharmacological antagonism reduces body weight and adiposity in the context of nutrient excess....

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Detalles Bibliográficos
Autores principales: Svendsen, Berit, Capozzi, Megan E., Nui, Jingjing, Hannou, Sarah A., Finan, Brian, Naylor, Jacqueline, Ravn, Peter, D'Alessio, David A., Campbell, Jonathan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939028/
https://www.ncbi.nlm.nih.gov/pubmed/32029229
http://dx.doi.org/10.1016/j.molmet.2019.11.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939028/
https://www.ncbi.nlm.nih.gov/pubmed/32029229
http://dx.doi.org/10.1016/j.molmet.2019.11.018

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