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Is the sigma-1 receptor a potential pharmacological target for cardiac pathologies? A systematic review

Sigma-1 receptors are ligand-regulated chaperone proteins, involved in several cellular mechanisms. The aim of this systematic review was to examine the effects that the sigma-1 receptor has on the cardiovascular system. The interaction targets and proposed mechanisms of action of sigma-1 receptors...

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Detalles Bibliográficos
Autores principales: Lewis, Rebecca, Li, Jiaqi, McCormick, Peter J, L-H Huang, Christopher, Jeevaratnam, Kamalan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939113/
https://www.ncbi.nlm.nih.gov/pubmed/31909177
http://dx.doi.org/10.1016/j.ijcha.2019.100449