RNA toxicity in non‐coding repeat expansion disorders

Several neurodegenerative disorders like amyotrophic lateral sclerosis (ALS) and spinocerebellar ataxia (SCA) are caused by non‐coding nucleotide repeat expansions. Different pathogenic mechanisms may underlie these non‐coding repeat expansion disorders. While gain‐of‐function mechanisms, such as to...

Descripción completa

Detalles Bibliográficos
Autores principales: Swinnen, Bart, Robberecht, Wim, Van Den Bosch, Ludo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939197/
https://www.ncbi.nlm.nih.gov/pubmed/31721251
http://dx.doi.org/10.15252/embj.2018101112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939197/
https://www.ncbi.nlm.nih.gov/pubmed/31721251
http://dx.doi.org/10.15252/embj.2018101112

Ejemplares similares