Biologically indeterminate yet ordered promiscuous gene expression in single medullary thymic epithelial cells

To induce central T‐cell tolerance, medullary thymic epithelial cells (mTEC) collectively express most protein‐coding genes, thereby presenting an extensive library of tissue‐restricted antigens (TRAs). To resolve mTEC diversity and whether promiscuous gene expression (PGE) is stochastic or coordina...

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Detalles Bibliográficos
Autores principales: Dhalla, Fatima, Baran‐Gale, Jeanette, Maio, Stefano, Chappell, Lia, Holländer, Georg A, Ponting, Chris P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939203/
https://www.ncbi.nlm.nih.gov/pubmed/31657037
http://dx.doi.org/10.15252/embj.2019101828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939203/
https://www.ncbi.nlm.nih.gov/pubmed/31657037
http://dx.doi.org/10.15252/embj.2019101828

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