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Exploring Relationships between the Density of Charged Tracts within Disordered Regions and Phase Separation

Biomolecular condensates form through a process termed phase separation and play diverse roles throughout the cell. Proteins that undergo phase separation often have disordered regions that can engage in weak, multivalent interactions; however, our understanding of the sequence grammar that defines...

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Detalles Bibliográficos
Autores principales: Somjee, Ramiz, Mitrea, Diana M., Kriwacki, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939312/
https://www.ncbi.nlm.nih.gov/pubmed/31797598