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Proteoglycan serglycin promotes non-small cell lung cancer cell migration through the interaction of its glycosaminoglycans with CD44

BACKGROUND: Serglycin (SRGN), previously recognized as an intracellular proteoglycan involved in the storage processes of secretory granules, has recently been shown to be upregulated in several solid tumors. We have previously shown that SRGN in non-small cell lung cancer (NSCLC) promotes malignant...

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Detalles Bibliográficos
Autores principales: Guo, Jing-You, Chiu, Chu-Hsuan, Wang, Mei-Jung, Li, Fu-An, Chen, Jeou-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939340/
https://www.ncbi.nlm.nih.gov/pubmed/31898491
http://dx.doi.org/10.1186/s12929-019-0600-3