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Tissue-Resident Memory T Cells Mediate Immune Homeostasis in the Human Pancreas through the PD-1/PD-L1 Pathway

Non-recirculating tissue-resident memory T cells (TRMs) are the predominant T cell subset in diverse tissue sites, where they mediate protective immune responses in situ. Here, we reveal a role for TRM in maintaining immune homeostasis in the human pancreas through interactions with resident macroph...

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Detalles Bibliográficos
Autores principales: Weisberg, Stuart P., Carpenter, Dustin J., Chait, Michael, Dogra, Pranay, Gartrell-Corrado, Robyn D., Chen, Andrew X., Campbell, Sean, Liu, Wei, Saraf, Pooja, Snyder, Mark E., Kubota, Masaru, Danzl, Nichole M., Schrope, Beth A., Rabadan, Raul, Saenger, Yvonne, Chen, Xiaojuan, Farber, Donna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939378/
https://www.ncbi.nlm.nih.gov/pubmed/31851923
http://dx.doi.org/10.1016/j.celrep.2019.11.056