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Tissue-Resident Memory T Cells Mediate Immune Homeostasis in the Human Pancreas through the PD-1/PD-L1 Pathway
Non-recirculating tissue-resident memory T cells (TRMs) are the predominant T cell subset in diverse tissue sites, where they mediate protective immune responses in situ. Here, we reveal a role for TRM in maintaining immune homeostasis in the human pancreas through interactions with resident macroph...
Autores principales: | Weisberg, Stuart P., Carpenter, Dustin J., Chait, Michael, Dogra, Pranay, Gartrell-Corrado, Robyn D., Chen, Andrew X., Campbell, Sean, Liu, Wei, Saraf, Pooja, Snyder, Mark E., Kubota, Masaru, Danzl, Nichole M., Schrope, Beth A., Rabadan, Raul, Saenger, Yvonne, Chen, Xiaojuan, Farber, Donna L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939378/ https://www.ncbi.nlm.nih.gov/pubmed/31851923 http://dx.doi.org/10.1016/j.celrep.2019.11.056 |
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