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Inhibition of Disruptor of Telomeric Silencing 1-Like Alleviated Renal Ischemia and Reperfusion Injury-Induced Fibrosis by Blocking PI3K/AKT-Mediated Oxidative Stress

BACKGROUND: Ischemia/reperfusion (I/R) injury is a major cause of acute kidney injury, usually occurs during renal surgeries, and may eventually lead to chronic kidney diseases. However, effective therapeutic targets for renal I/R injury remain limited. PURPOSE: In the present study, we investigated...

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Detalles Bibliográficos
Autores principales: Yang, Chuan, Chen, Zhiyuan, Yu, Hua, Liu, Xiuheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939406/
https://www.ncbi.nlm.nih.gov/pubmed/31920287
http://dx.doi.org/10.2147/DDDT.S224909