Oncogenic D816V-KIT signaling in mast cells causes persistent IL-6 production

Persistent dysregulation of IL-6 production and signaling have been implicated in the pathology of various cancers. In systemic mastocytosis, increased serum levels of IL-6 associate with disease severity and progression, although the mechanisms involved are not well understood. Since systemic masto...

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Detalles Bibliográficos
Autores principales: Tobío, Araceli, Bandara, Geethani, Morris, Denise A., Kim, Do-Kyun, O’Connell, Michael P., Komarow, Hirsh D., Carter, Melody C., Smrz, Daniel, Metcalfe, Dean D., Olivera, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939509/
https://www.ncbi.nlm.nih.gov/pubmed/30948489
http://dx.doi.org/10.3324/haematol.2018.212126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939509/
https://www.ncbi.nlm.nih.gov/pubmed/30948489
http://dx.doi.org/10.3324/haematol.2018.212126

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