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Oncogenic D816V-KIT signaling in mast cells causes persistent IL-6 production

Persistent dysregulation of IL-6 production and signaling have been implicated in the pathology of various cancers. In systemic mastocytosis, increased serum levels of IL-6 associate with disease severity and progression, although the mechanisms involved are not well understood. Since systemic masto...

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Detalles Bibliográficos
Autores principales:	Tobío, Araceli, Bandara, Geethani, Morris, Denise A., Kim, Do-Kyun, O’Connell, Michael P., Komarow, Hirsh D., Carter, Melody C., Smrz, Daniel, Metcalfe, Dean D., Olivera, Ana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ferrata Storti Foundation 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939509/ https://www.ncbi.nlm.nih.gov/pubmed/30948489 http://dx.doi.org/10.3324/haematol.2018.212126

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