Cargando…

Myeloid differentiation factor 88 signaling in donor T cells accelerates graft-versus-host disease

Myeloid differentiation factor 88 (MyD88) signaling has a crucial role in activation of both innate and adoptive immunity. MyD88 transduces signals via Toll-like receptor and interleukin-1 receptor superfamily to the NFκB pathway and inflammasome by forming a molecular complex with interleukin-1 rec...

Descripción completa

Detalles Bibliográficos
Autores principales: Matsuoka, Satomi, Hashimoto, Daigo, Kadowaki, Masanori, Ohigashi, Hiroyuki, Hayase, Eiko, Yokoyama, Emi, Hasegawa, Yuta, Tateno, Takahiro, Chen, Xuanzhong, Aoyama, Kazutoshi, Oka, Hideyo, Onozawa, Masahiro, Takeda, Kiyoshi, Akashi, Koichi, Teshima, Takanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939524/
https://www.ncbi.nlm.nih.gov/pubmed/31048358
http://dx.doi.org/10.3324/haematol.2018.203380